There are three main areas to explore: the Nossop River valley, along the South Africa/Botswana border, the wilderness trails on the Botswana side, and what was once the Mabuasehube Game Reserve, now incorporated into KTP at its most northeastern reaches. KTP’s very beautiful terrain comprises fossil river valleys dotted with dwarfed trees and bushes, grasslands and different coloured sand dunes. Wildlife is abundant, and the animals are attracted to waterholes along the otherwise dry riverbed such as antelope, including the ubiquitous springbok and gemsbok, hartebeest, and eland can be seen, as well as the famous black-maned Kalahari lion, jackal, brown hyena, and wild cats.Rich birding is always part of the experience. Over 170 species of birds have been recorded here.

At Mabuasehube, the terrain is a mixture of typical Kgalagadi tree and shrub savanna with patches of wide open grass savanna. This area of KTP comprises a series of exceptionally large pans, which are the principle focus of the reserve. Three of the largest pans lie along the main road; these are Bosobogolo, Mpayathutlwa and Mabuasehube. All of the major predators can be seen at Mabuasehube, including the Kalahari black-maned lion, cheetah, leopard, brown hyena, bat-eared fox, lynx, and silver fox. Small mammals, like the Cape fox, aardwolf and blackfooted cat can be seen at the pans in the evening.